I develop and perform standard and bespoke analyses for customers, collaborators, compatible business partners, and internal teams to support instrument and consumable sales, product validation, and marketing collateral.

• supported development and refinement of tools and workflows for various HiFi applications such as CiFi and microbial isolate sequencing
• contributed to instrument and consumable sales by delivering high-quality data with rapid turnaround times and comprehensible bioinformatics guidance
• performed reproducible, highly documented validation tests in advance of launching new products such as SPRQ-Nx
• showcased the performance of HiFi sequencing by contributing bioinformatics analyses to collaborator publications and generating marketing datasets and visualizations
• built and maintained project management and reporting systems for the applications lab to enable both small- and large-scale sequencing projects such as our collaboration with Basecamp Research on the Trillion Gene Atlas Initiative

• developed a database of human variation from HiFi whole genome sequencing (WGS) in 1000+ samples as part of the Consortium of Long Read Sequencing
• developed tertiary analysis tools (variant annotation and prioritization) to complement HiFi-specific variants callers
• evaluated and guided development of external HiFi-compatible biological interpretation and tertiary analysis tools
• worked with NIST Genome in a Bottle to improve human variant calling benchmarks

• supported commercial teams by leveraging pilot experiments into instrument sales and marketing collateral
• developed workflows for variant calling, filtering, annotation, and prioritization for rare and inherited disease studies

Investigated the etiology and pathogenesis of wooden breast (WB) and white striping (WS), two novel and related complex muscle disorders in commercial broiler chickens that cause major economic losses and welfare concerns worldwide.

• developed computational pipelines and machine learning models for analysis of NGS (DNA & RNA) and proteomics data
• proposed a completely new hypothesis linking recently emerged muscle disorders like WB and WS in chickens with type II diabetes in humans
• designed and conducted experiments involving genome-wide association (GWA), differential gene expression (RNA-Seq), and biomarker identification

Studied resistance to and transmission of rose rosette disease (RRD), a fatal and widespread disease of landscape roses caused by the multipartite emaravirus rose rosette virus (RRV) vectored by the eriophyid mite Phyllocoptes fructiphilus.

• managed a large, randomized field trial to screen rose genotypes for resistance to RRD
• tested the effectiveness of biological control methods in mitigating spread of the vector mite P. fructiphilus for potential use in greenhouse grow operations